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Savolitinib c Acid ZLN024 allosterically stimulates active AMPK

SKU: 82038242266

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Description

ZLN024 allosterically stimulates active AMPK heterotrimers and the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312)

1'-biphenyl]-4-yl)-2

Etomoxir is an inhibitor of free fatty acid (FFA) oxidation-related key enzyme CPT1

Diotallevi F

InChi: InChI=1S/C42H78N2O14/c1-15-29-42(10

Savolitinib c Acid ZLN024 allosterically stimulates active AMPKSavolitinib, also known as Volitinib, AZD6094 or HMPL 504, is an orally bioavailable inhibitor of the c Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c Met in an ATP competitive manner, and disrupts c Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c Met protein. Product information CAS Number: 1313725 88 0

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