TC-G 1004 Catalog No.:M20085-C AGN193109 half-reverses retinoid-dependent growth suppression

AGN193109 half-reverses retinoid-dependent growth suppression at 10 nM

and increased hotplate latency in nicotine withdrawn mice following pre-treatment

8S)-4-{[4-(cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-11-azatricyclo[6

and LAT2 at 10 μM

a component isolated from Polygalae Radix

TC-G 1004 Catalog No.:M20085-C AGN193109 half-reverses retinoid-dependent growth suppressionTC G 1004 (compound 16j) is an orally active A2A adenosine receptor antagonist, with Ki values of 0. 44 nM and 80 nM for hA2A and hA1, respectively. Product information CAS Number: 1061747 72 5 Molecular Weight: 421. 50 Formula: C22H27N7O2 Chemical Name: N [2 (3,5 dimethyl 1H pyrazol 1 yl) 6 [6 (4 methoxypiperidin 1 yl)pyridin 2 yl]pyrimidin 4 yl]acetamide Smiles: CC1C=C(C)N(N=1)C1N=C(C=C(NC(C)=O)N=1)C1=CC=CC(=N1)N1CCC(CC1)OC InChiKey: JENSDTKXNVHSSN