BAY-985 Catalog No.:M7451-2 Smiles: CN(C)CC(=O)NC[C@H](CC1C=CC(=CC=1)C1=CN2C=CC=C([C@H](C)O)C2=N1)NC(=O)C1=CC(Cl)=C(C=C1)OC(C)C

Smiles: CN(C)CC(=O)NC[C@H](CC1C=CC(=CC=1)C1=CN2C=CC=C([C@H](C)O)C2=N1)NC(=O)C1=CC(Cl)=C(C=C1)OC(C)C

Sirtinol significantly increased the acetylation of p53

16(6):922-32

CPI-444 is a potent

WO 2010022355 A1 20100225

BAY-985 Catalog No.:M7451-2 Smiles: CN(C)CC(=O)NC[C@H](CC1C=CC(=CC=1)C1=CN2C=CC=C([C@H](C)O)C2=N1)NC(=O)C1=CC(Cl)=C(C=C1)OC(C)CBAY 985 is a potent and highly selective TBK1 IKK inhibitor. BAY 985 shows high potency toward TBK1 (IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKK(IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK MEL 2 cells (IC50 = 900 nM). Product information CAS Number: 2409479 29 2 Molecular Weight: 553. 58 Formula: C27H30F3N9O Chemical Name: 1 (4 {(1R) 1 [2 ({6 [6