Pay in 4 interest-free payments of $11.25 Learn more
Ships within 48 hours · Estimated delivery Jul 29 - Aug 3
159(6):1236-46
CAS Number: 1169755-45-6
58 μM achieved at 1
and augmented animal survival
Chemical Name: (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5
R-(+)-ETOMOXIR - CAS# 124083-20-1 093 159(6):1236-46R (+) ETOMOXIR, CAS No. 124083 20 1, is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT 1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as