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CGH 2466 dihydrochloride 485luxametamide CAS Number: 2158266-58-9

SKU: 18404894202

4.3
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Description

CAS Number: 2158266-58-9

InChiKey: ACOXQYLJOQAHST-ZDUSSCGKSA-N

Chemical Name: 3-hydroxypentanoic acid

Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells

Solubility: DMSO: 36 mg/mL(199

CGH 2466 dihydrochloride 485luxametamide CAS Number: 2158266-58-9CGH 2466 dihydrochloride is a combined adenosine receptor antagonist. It is an inhibitor of phosphodiesterase type 4 and p38 mitogen activated protein kinase. It inhibited the phosphodiesterase 4D (PDE4D) isoenzyme with an IC50 value of 225 nM. It inhibited the p38 mitogen activated protein (MAP) kinases and with IC50 values of 18718, 40038 nM, respectively . There are four adenosine receptor subtypes of the G protein coupled receptor family,

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