(R, S)-Ivosidenib er Conjugate 5 Chemical Name: 4-{4-[(5-fluoro-4-{[3-(prop-2-enamido)phenyl]amino}pyrimidin-2-yl)amino]phenoxy}-N-methylpyridine-2-carboxamide

Chemical Name: 4-{4-[(5-fluoro-4-{[3-(prop-2-enamido)phenyl]amino}pyrimidin-2-yl)amino]phenoxy}-N-methylpyridine-2-carboxamide

Dosing is stopped at study Day 16 and all 4 mice in the 100 mg/kg cohort and 2 out of 7 mice in the 30 mg/kg cohort remains tumor-free through study Day 70

Formula: C18H13N7

Monastrol is a small

SB297006 is a CCR3 antagonist

(R, S)-Ivosidenib er Conjugate 5 Chemical Name: 4-{4-[(5-fluoro-4-{[3-(prop-2-enamido)phenyl]amino}pyrimidin-2-yl)amino]phenoxy}-N-methylpyridine-2-carboxamide(R,S) Ivosidenib ((R,S) AG 120) is the less active enantiomer of Ivosidenib (AG 120). Product information CAS Number: 2070009 31 1 Molecular Weight: 582. 96 Formula: C28H22ClF3N6O3 Chemical Name: (2R) 2 (2 chlorophenyl) 2 {1 [(2S) 1 (4 cyanopyridin 2 yl) 5 oxopyrrolidin 2 yl] N (5 fluoropyridin 3 yl)formamido} N (3,3 difluorocyclobutyl)acetamide Smiles: N#CC1C=CN=C(C=1)N1[C@@H](CCC1=O)C(=O)N([C@H](C1=CC=CC=C1Cl)C(=O)NC1CC(F)(F)C1)C1=CC(F)=CN=C1