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arrest the cell cycle
InChi: InChI=1S/C20H13NO5/c22-20-12-5-10-2-4-15-19(26-9-24-15)18(10)17(13(12)7-21-20)11-1-3-14-16(6-11)25-8-23-14/h1-6H
with IC(50) values well above concentrations anticipated to be achieved in vivo
NP118809 further exhibits a number of favorable preclinical characteristics as they relate to overall pharmacokinetics and minimal off-target activity including the hERG potassium channel
Smiles: N[C@@](CCN1CCCCC1)(CCCCB(O)O)C(O)=O
KN-92 - CAS# 176708-42-2 or KRAS arrest the cell cycleKN 92 is an inactive analog of the CaM kinase II inhibitor KN 93. Product information CAS Number: 176708 42 2 Molecular Weight: 456. 98 Formula: C24H25ClN2O3S Synonym: KN 92 KN92 Chemical Name: N [2 ({[(2E) 3 (4 chlorophenyl)prop 2 en 1 yl](methyl)amino}methyl)phenyl] 4 methoxybenzene 1 sulfonamide Smiles: COC1C=CC(=CC=1)S(=O)(=O)NC1=CC=CC=C1CN(C)C C=C C1C=CC(Cl)=CC=1 InChiKey: RUAOVVIUGUOYHA AATRIKPKSA N InChi: InChI=1S C24H25ClN2O3S c1 27(17 5 6 19
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