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InChiKey: QBIYUDDJPRGKNJ-UHFFFAOYSA-M
and inhibits the growth of two xenografted tumors in mice in vivo
a novel transforming growth factor beta receptor type I and type II dual inhibitor
4-dihydro-1
1351761-44-8
CID-2011756 - CAS# 638156-11-3 und Library of Histone Demethylase InChiKey: QBIYUDDJPRGKNJ-UHFFFAOYSA-MCID 2011756, CAS No. 638156 11 3, is a cell active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester induced endogenous PKD1 activation in LNCaP prostate cancer cells. IC50 Value: 100. 7 uM (cellular inhibition of phospho Ser916 PKD1 activity) [1] Target: PKD CID 2011756, has pan PKD inhibitory effects (PKD2 IC50 = 0. 60. 1 uM; PKD3 IC50 = 0. 70. 2 uM) with similar, albeit not identical, potencies which may be expected for an ATP
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