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A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models
Chemical Name: methyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1
BFH772 is highly selective
18R)-14-{[(cyclopentyloxy)carbonyl]amino}-18-[(7-methoxy-2-{2-[(propan-2-yl)amino]-1
) increases the level of leucine from 473 μM to 1
OT antagonist 1 Catalog No.:M20631-C A selective inhibitor of PRMT5OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM. Product information CAS Number: 479080 38 1 Molecular Weight: 390. 44 Formula: C22H22N4O3 Chemical Name: (3E,5S) N methoxy 5 (3 methyl 1,2,4 oxadiazol 5 yl) 1 {2' methyl [1,1' biphenyl] 4 carbonyl}pyrrolidin 3 imine Smiles: CO N=C1\C[C@@H](C2=NC(C)=NO2)N(C\1)C(=O)C1C=CC(=CC=1)C1=CC=CC=C1C InChiKey: PFGOHCJFGDEHAX HBTCSRNFSA N InChi: InChI=1S C22H22N4O3 c1 14 6
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