PJ34 - CAS# 344458-19-1 e O-desmethyl Mebeverine acid Formula: C18H20O2

Formula: C18H20O2

Rottlerin (20 μM

Ennaceur A

It belongs to a class of antiplatelet named glycoprotein IIb/IIIa inhibitors

resulting in activation of tumor suppressor pathways and concurrent inhibition of several oncogenic pathways

PJ34 - CAS# 344458-19-1 e O-desmethyl Mebeverine acid Formula: C18H20O2PJ 34 is a novel and potent PARP 1 inhibitor with potential anticancer activity. PJ34 has a high affinity for PARP 1 (IC(50) = 20 nM). PJ 34 inhibits PARP 1 expression and ERK phosphorylation in glioma conditioned brain microvascular endothelial cells. PJ 34 reduces mesenteric vascular injury induced by experimental cardiopulmonary bypass with cardiac arrest. PJ 34 reduce cell inflammation and damage that follow PARP 1 overexpression. PJ 34 negatively