Pay in 4 interest-free payments of $20.00 Learn more
Ships within 48 hours · Estimated delivery Jul 27 - Aug 1
Jian-Ting Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation
In glioblastoma cells
is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM
InChi: InChI=1S/C21H22O8/c1-23-13-8-7-11(9-15(13)24-2)14-10-12(22)16-17(25-3)19(26-4)21(28-6)20(27-5)18(16)29-14/h7-10H
Smiles: CCC1=C(CC(=O)N(CCOC)CCOC)C(C(=O)C2=CC(OC)=C(C=C2)OCCN2CCOCC2)=C(O)C=C1O
Vinblastine sulfate Size:Solid 2 mg Jian-Ting Synthesis and Identification ofVinblastine is a natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin dependent Ca++ transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.
US$ 28.00
US$ 3334.97
US$ 68.00
US$ 140.00
US$ 145.00