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OSI-027 was orally dosed to mice at 50-65 mg/kg once per day
Melania Guerrero Hue
D-2-Hydroxypentanedioic acid-2Na+
301353-96-8
477600-75-2
1-methyl-D-tryptophan (D-1MT) - IDO Inhibitor. CAS# 110117-83-4 size:2 mg solid OSI-027 was orally dosed to1 methyl D tryptophan (D 1MT) , CAS No. 110117 83 4, is a potent and selective indoleamine 2, 3 dioxygenase (IDO) inhibitor with IC50 ~7 M. It disrupts tryptophan catabolism and enhances the antitumor and antiviral immunoresponses of CD8+ T cells in vitro. It can reduce tumor volume in mice with xenografts overexpressing IDO. Product information CAS Number: 110117 83 4 Molecular Weight: 218. 25 Formula: C12H14N2O2 Synonym: D 1MT 1 MT 1 Methyl D
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