PS 1145 dihydrochloride 710ROTAC BRD2/BRD4 degrader-1 causes a dose dependent tumour

causes a dose dependent tumour static effect that can be converted into regressions when combined with MEK1 inhibition

and up-regulates spot 6507 (collapsin response mediator protein 1) in mouse cortical neurons

53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29

2-diphenylpentanenitrile hydrochloride

30)5)57-42-39(61-40-35(52)33(50)31(48)21(3)56-40)37(54)38(29(17-47)59-42)60-41-36(53)34(51)32(49)28(16-46)58-41/h6

PS 1145 dihydrochloride 710ROTAC BRD2/BRD4 degrader-1 causes a dose dependent tumourProduct information CAS Number: 1049743 58 9 Molecular Weight: 395. 67 Formula: C17H13Cl3N4O Chemical Name: (Z) N {6 chloro 9H pyrido[3,4 b]indol 8 yl}pyridine 3 carboximidic acid dihydrochloride Smiles: Cl. Cl. O C(=N\C1C=C(Cl)C=C2C=1NC1=CN=CC=C21) C1=CN=CC=C1 InChiKey: QTDCBADLGJZBHP UHFFFAOYSA N InChi: InChI=1S C17H11ClN4O. 2ClH c18 11 6 13 12 3 5 20 9 15(12)21 16(13)14(7 11)22 17(23)10 2 1 4 19 8 10;; h1 9,21H,(H,22,23); 2*1H Technical Data