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RAS inhibitor Abd-7 Size:Contact [email protected] for quotation 4 ng/mL) incubation induces apoptosis

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Description

4 ng/mL) incubation induces apoptosis and increases leakage of lactate dehydrogenase (LDH) in HepG2 cells

InChi: InChI=1S/C21H23ClN2O2

Chemical Name: 2-(4-{4-[(5S)-5-(acetamidomethyl)-2-oxo-1

PF-04979064 is the back-up candidate to PF-04691502 which is in Phase I/II clinical trials for treating solid tumors

Energy conversion efficiencies greater than 50% are achievable

RAS inhibitor Abd-7 Size:Contact [email protected] for quotation 4 ng/mL) incubation induces apoptosisRAS inhibitor Abd 7, a potent RAS binding compound (Kd=51 nM), is a RAS effector protein protein interaction (PPI) inhibitor. RAS inhibitor Abd 7 interacts with RAS inside the cells, prevents RAS effector interactions and inhibits endogenous RAS dependent signaling. RAS inhibitor Abd 7 impairs the PPI of various mutant KRAS proteins with PI3K, CRAF and RALGDS as well as NRAS Q61H and HRAS G12V. Product information CAS Number: 2351843 48 4 Molecular

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