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NCGC00402261-03
TYP inhibits melatonin-enhanced SIRT3 activity but does not affect SIRT3 protein expression
AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation
is a heterobifunctional linker
PubMed PMID: 24106120
Stattic Size:10mg solid NCGC00402261-03Stattic is a potent STAT3 inhibitor and inhibits STAT3 phosphorylation (at Y705 and S727). Stattic inhibits the binding of a high affinity phosphopeptide for the SH2 domain of STAT3. Stattic ameliorates the renal dysfunction in Alport syndrome (AS) mice. Product information CAS Number: 19983 44 9 Molecular Weight: 211. 19 Formula: C8H5NO4S Chemical Name: 6 nitro 1 benzothiophene 1, 1 dione Smiles: [O ][N+](=O)C1=CC2=C(C=CS2(=O)=O)C=C1 InChiKey:
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