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SC144 treatment eventually causes cell-cycle arrest
The knock-down of MKP-1 using specific si-RNA restores the reduced VSMC viability by Tauroursodeoxycholate (200 μM)
InChi: InChI=1S/C26H21N3O4/c1-25-26(32
Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1)C(=O)NCCOCCOCCNC(=O)C1=CC=C(C=C1)C1=NC(CNC2=NC=CC(NCC(C)C)=N2)=CS1
The cytotoxic concentration-50% (CC50) is therefore>100 μM
N3-PEG3-CH2CH2-Boc ramin-1 SC144 treatment eventually causes cell-cycleN3 PEG3 CH2CH2 Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody drug conjugates (ADCs). N3 PEG3 CH2CH2 Boc is also a PEG and Alkyl ether based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 252881 73 5 Molecular Weight: 303. 35 Formula: C13H25N3O5 Chemical Name: tert butyl 3 {2 [2 (2 azidoethoxy)ethoxy]ethoxy}propanoate Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCN=[N+]=[N ] InChiKey:
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