Bosutinib hydrate Size:Contact [email protected] for quotation 1'-biphenyl]-4-yl}sulfonyl)methyl]-2-hydroxy-3-(phenylsulfanyl)propanoic acid sodium

1'-biphenyl]-4-yl}sulfonyl)methyl]-2-hydroxy-3-(phenylsulfanyl)propanoic acid sodium

6-tetrahydropyridine (MPTP) -induced depletion of glutathione

Formula: C27H30F6N2O2

InChi: InChI=1S/C30H46O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3

4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-5-oxopentane-1-guanidine

Bosutinib hydrate Size:Contact [email protected] for quotation 1'-biphenyl]-4-yl}sulfonyl)methyl]-2-hydroxy-3-(phenylsulfanyl)propanoic acid sodiumBosutinib, also known as SKI 606, is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Unlike imatinib, bosutinib inhibits the autophosphorylation of both Abl and Src kinases, resulting in inhibition of cell growth and apoptosis. Because of the dual mechanism of action, this agent may have activity in resistant CML disease, other myeloid malignancies and solid