TAK1/MAP4K2 inhibitor 1 roacetate salt Smiles: CC1=C(/C=C2/C3=CC(F)=CC=C3NC/2=O)NC(C)=C1C(=O)NCCN1CCCC1

Smiles: CC1=C(/C=C2/C3=CC(F)=CC=C3NC/2=O)NC(C)=C1C(=O)NCCN1CCCC1

and MDA-MB-361 cells with IC50 of 46 nM

CAS Number: 1435488-37-1

SR-01000909725-1

Ex vivo studies showed that pantoprazole inhibited TOPK activities in JB6 Cl41 cells and HCT 116 colorectal cancer cells

TAK1/MAP4K2 inhibitor 1 roacetate salt Smiles: CC1=C(/C=C2/C3=CC(F)=CC=C3NC/2=O)NC(C)=C1C(=O)NCCN1CCCC1TAK1 MAP4K2 inhibitor 1 is a potent dual TGF activated kinase 1 (TAK1) and mitogen activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC50s of 41. 1 nM and 18. 2 nM, respectively. Product information CAS Number: 1315330 11 0 Molecular Weight: 552. 59 Formula: C29H31F3N6O2 Synonym: Benzamide, N [4 [(4 ethyl 1 piperazinyl)methyl] 3 (trifluoromethyl)phenyl] 4 methyl 3 [(6 methyl 7H pyrrolo[2,3 d]pyrimidin 4 yl)oxy] Chemical Name: N