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Chemical Name: 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol
is a potent and selective ALK inhibitor
LW8 was found to inhibits the accumulation of HIF-1alpha
Chemical Name: 4-(benzylamino)-2-{[2-(3-chloro-4-hydroxyphenyl)ethyl]amino}pyrimidine-5-carboxamide
which corresponds to the gatekeeper mutation conferring common resistance to kinase inhibitors
Osimertinib D6 - CAS# 1638281-44-3 n 15 Chemical Name: 2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-olOsimertinib D6 (AZD 9291 D6) is a deuterium labeled Osimertinib. Osimertinib is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R T790M, respectively. Product information CAS Number: 1638281 44 3 Molecular Weight: 505. 64 Formula: C28H33N7O2 Synonym: AZD 9291 D6 Mereletinib D6 Chemical Name: N [2 ({2 [di(H)methylamino]ethyl}(methyl)amino) 4 methoxy 5 {[4 (1 methyl 1H indol 3 yl)pyrimidin 2