NVP-BHG712 Catalog No.:M7900-2 Smiles: [O-][N+](=O)C1=CC(Cl)=CC=C1S(=O)(=O)C1C=CC=CC=1

Smiles: [O-][N+](=O)C1=CC(Cl)=CC=C1S(=O)(=O)C1C=CC=CC=1

Shchepina LA

PIK-294 inhibits both chemokinetic and chemotactic CXCL8-induced migration

Porchia LM

Smiles: CC(C)C1=CC=CC=C1CC1=CC(C(=O)NC2C=CC(=CC=2)S(=O)(=O)C2=CC=CC=C2C(C)(C)C)=C(O)C(O)=C1O

NVP-BHG712 Catalog No.:M7900-2 Smiles: [O-][N+](=O)C1=CC(Cl)=CC=C1S(=O)(=O)C1C=CC=CC=1NVP BHG712, also known as BHG 712, is a EphB4 kinase inhibitor and BCR ABL inhibitor. NVP BHG712, which inhibits EphB4 kinase activity in the low nanomolar range in cellular assays showed high selectivity for targeting the EphB4 kinase when profiled against other kinases in biochemical as well as in cell based assays. BHG 712 shows excellent pharmacokinetic properties and potently inhibits EphB4 autophosphorylation in tissues after oral