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pMEK (A375) IC50
InChiKey: HDLNHPZHTNFCNP-JJEFWQELSA-N
Chemical Name: (E)-N-cyclohexyl-N''-(2-methylquinolin-4-yl)-N'-(1
Formula: C8H16BrNO2
in non-small cell lung cancer cell lines
MID-1 O-isobutyryl-12-O-acetyltenacigenin B pMEK (A375) IC50MID 1 is a disruptor of MG53 IRS 1 (Mitsugumin 53 insulin receptor substrate 1) interaction. MID 1 disrupts molecular association of MG53 with IRS 1 and abolishes MG53 induced IRS 1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS 1 expression level and increased insulin signaling and glucose uptake. Product information CAS Number: 312608 54 1 Molecular Weight: 293. 30 Formula: C12H11N3O4S Chemical Name: 4 ethoxy N (5 nitro
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