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InChi: InChI=1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7
Molecular Weight: 187
1007/BF02924157
or EBC1 (non-amplified
The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models
Maraviroc revir InChi: InChI=1S/C19H17Cl3N4O3/c1-28-8-9-29-19-24-18(12-2-7-15(21)16(22)10-12)26(25-19)14-5-3-13(4-6-14)23-17(27)11-20/h2-7Maraviroc is an antiviral, potent, non competitive CKR 5 receptor antagonist that inhibits binding of HIV viral coat protein gp120. Maraviroc inhibits MIP 1 stimulated S GTP binding to HEK 293 cell membranes, indicating its ability to inhibit chemokine dependent stimulation of GDP GTP exchange at the CKR 5 G protein complex. Maraviroc also inhibits the downstream event of chemokine induced intracellular calcium redistribution. Product information CAS
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