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Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents
RBC8 suppresses growth of xenograft tumors in mice
and improves lipid profile
LJI308 inhibits S6K1 with an IC50 of 0
COX/5-LO-IN-1 (Atreleuton analog) is an inhibitor of cylooxygenase and 5-lipoxygenase (5-LO)
(Rac)-BAY-985 Catalog No.:M15667-C Novel SHP-1 inhibitors tyrosine phosphatase(Rac) BAY 985 (Compound Example 100. 01) is a potent, ATP competitive and selective TBK1 inhibitor with an IC50 of 1. 5 nM. Antitumor efficacy. Product information CAS Number: 2101925 20 4 Molecular Weight: 553. 58 Formula: C27H30F3N9O Chemical Name: 1 (4 {1 [2 ({6 [6 (dimethylamino)pyrimidin 4 yl] 1H 1,3 benzodiazol 2 yl}amino)pyridin 4 yl]ethyl}piperazin 1 yl) 3,3,3 trifluoropropan 1 one Smiles:
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