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Batefenterol (GSK961081
Ali S et al
4 nM (PKC-ε) and 1 nM (PKC-μ) in HOP-92 cells
InChi: InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4
a flavonol glycoside found in many plants including buckwheat
KRM-III medastine Batefenterol (GSK961081KRM III is a potent and orally active T cell antigen receptor (TCR) inhibitor. KRM III inhibits TCR and phorbol myristate acetate ionomycin induced activation of nuclear factor of activated T cells (NFAT) and T cell proliferation with an IC50 of ~5 M. Anti inflammatory activity. Product information CAS Number: 79220 94 3 Molecular Weight: 252. 33 Formula: C15H12N2S Chemical Name: 1,4 diphenyl 2,3 dihydro 1H imidazole 2 thione Smiles: