Teriflunomide impurity 3 Catalog No.:M32043-C Smiles: CC1=N[C@]2(N=C1N)C1C=C(C=CC=1C[C@@]12CC[C@H](CC1)OC)C1=CN=CC(=C1)C#CC

Smiles: CC1=N[C@]2(N=C1N)C1C=C(C=CC=1C[C@@]12CC[C@H](CC1)OC)C1=CN=CC(=C1)C#CC

Formula: C22H23F3N4O4

InChi: InChI=1S/C18H24O3/c1-17-8-7-15-13(14(17)4-5-16(17)20)3-2-11-10-12(19)6-9-18(11

Treatment with J-113397 at increasing concentration shifted the concentration-response curve of nociceptinr/orphanin FQ to the right

3S)-2-[[(2S)-5-amino-2-[[(2S)-2-amino-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]acetyl]amino]acetyl]amino]-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid 2

Teriflunomide impurity 3 Catalog No.:M32043-C Smiles: CC1=N[C@]2(N=C1N)C1C=C(C=CC=1C[C@@]12CC[C@H](CC1)OC)C1=CN=CC(=C1)C#CCTeriflunomide impurity 3 (4 Amino N (4 trifluoromethylphenyl)benzamide) is a selective COX 1 inhibitor with an IC50 of 30 M. Teriflunomide impurity 3 is less active against COX 2 (IC50>100 M). Product information CAS Number: 1011244 72 6 Molecular Weight: 280. 25 Formula: C14H11F3N2O Chemical Name: 4 amino N [4 (trifluoromethyl)phenyl]benzamide Smiles: NC1C=CC(=CC=1)C(=O)NC1C=CC(=CC=1)C(F)(F)F InChiKey: YUWBBWHECQSIKL UHFFFAOYSA N InChi: InChI=1S