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It is the most widely used PI3K inhibitor to study the role of phosphoinositide 3-kinases in the signal transduction pathways involved in cell migration
Formula: C13H22Br2Cl2N2
Smiles: CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1
Int J Clin Pharmacol Ther
Formula: C25H28N6O
4SC-202 free base xiben HCl It is the most widelyDomatinostat, also known as 4SC 202, is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC 202 selectively binds to and inhibits class I HDACs leading to an accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the selective transcription of tumor suppressor genes, and the tumor
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